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 Current focus of interest is the role of clonal T cell and B cell populations in autoimmunity and cancer, quantitative analysis of individual T cell receptor and antibody repertoires in health and disease. The main goal is to understand the architecture of human adaptive immunity organisation in health and disease, in development and aging. Tools: high-throughput profiling of T cell receptor and antibody repertoires with the use of unique molecular identifiers (UMI), followed by advanced bioinformatics analysis.     

Research areas
The role of clonal populations of T cells and B cells in autoimmunity and cancer
DNA technologies and software development for quantitative analysis of individual T cell receptors and antibody repertoires in health and disease
Development of new methods for identifying PCR and sequencing errors
Development of new methods for analyzing high-throughput sequencing data
publications
Courses
publications