Ilya Mazunin's Group

The focus of our group is on human mitochondrial DNA (mtDNA) - the genetic program of eukaryotic cells located outside the nucleus, encoding the essential components of the oxidative phosphorylation complexes.

research areas

Developing an efficient and accessible tool for human mtDNA editing

Development of mitochondrial therapy aimed at reducing aneuploidy rates during oocyte in vitro maturation protocol

Team

Publications

Litvinova, L.S., Kirienkova, E.V., Mazunin, I.O., Vasilenko, M.A., Fattakhov, N.S. Pathogenesis of insulin resistance in metabolic obesity (2014) Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry, 8 (3), pp. 192-202.

Sokhonevich, N.A., Yurova, K.A., Gutsol, A.A., Khaziakhmatova, O.G., Mazunin, I.O., Litvinova, L.S. Effects of Immunoregulatory Cytokines (IL-2, IL-7, and IL-15) on Expression of Gfi1 and U2afll4 Genes in T Cells at Different Stages of Differentiation (2015) Bulletin of Experimental Biology and Medicine, 4 p.

Orishchenko, K.E., Sofronova, J.K., Chupakhin, E.G., Lunev, E.A., Mazunin, I.O. Delivery Cas9 into mitochondria (2016) Genes & Cells, XI (2), pp. 100-105

Mazunin I. Human mitochondrial genome surgery (2018) Genes & Cells (DOI: 10.23868/201811030)