Skolkovo Institute of Science and Technology
Evgeny Nikolaev’s group
The group includes two laboratories: the Laboratory of Mass Spectrometry and the Laboratory of Omics Technologies and Big Data for Personalized Medicine and Health.
Supercomputer modeling of ion clouds behavior in accumulation and transport mass spectrometer devices.
Quantitative mass spectrometry for personalized medicine.
Investigation of microgravity influence on astronaut’s body liquid proteome and metabolome by quantitative mass spectrometry.
Omics technologies.
Development and application of on fly H/D exchange methods.
Classification analysis of organic carbon natural storages using ultrahigh accuracy mass spectrometry (Fourier Transform Ion Cyclotron Resonance Mass Spectrometry)
Research areas
Creation of new types of mass spectrometers based on harmonized electrostatic Kingdon traps and other devices
Development of new methods for achieving ultra-high resolution mass spectrometers and ionization of molecules
Development of interfaces for mass spectrometry with atmospheric pressure ionization
Simulation of the movement of ion clouds in electric and magnetic fields
Development of mass spectrometers for wide analytical applications and, in particular, for space research
Biomedical applications of mass spectrometry, omics technologies
Development of methods for isolating proteins and metabolites from physiological fluids of humans and model animals
Development of methods for enzymatic digestion of proteins and methods for separation of peptides
Development of methods for the synthesis of peptide standards labeled with stable isotopes
Development of quantitative proteomics methods based on the use of isotope-labeled peptide standards